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Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C49H86N10O19 Molecular Weight 1119
DOTA bifucational chelator containing an azide group
Product Name Thalidomide-C3-PEG4-C2-Br Synonyms Thalidomide-4'-C3-PEG4-C2-Br CAS Number n/a Related CAS Molecular Formula C26H35BrN2O9 Molecular Weight 599
It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)
PEG3 linker enhances water solubility and provides spatial separation to minimize steric hindrance during binding interactions
Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB Size:100mg Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine
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